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KMID : 0980720120310020214
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Keimyung Medical Journal
2012 Volume.31 No. 2 p.214 ~ p.220
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Relation Between Pyuria and Intraprostatic Inflammation in Benign Prostatic Hyperplasia
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Ha Ji-Yong
Kim Byung-Hoon
Park Choal-Hee
Kim Chun-Il
Kwon Sun-Young
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Abstract
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Prostatic inflammation was determined to varying extents in the pathological specimens of patients who underwent transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH). However we did not know who had prostatic inflammation before we got pathological specimens. We therefore whether there is a relationship between degree of pyuria and prostatic inflammation. Between January 1997 and December 2006, a total of 221 patients underwent TURP due to BPH. The histopathologic results, including inflammatory patterns, the mean value of age, serum prostate specific antigen (PSA) level, prior α1-blocker and 5 alpha reductase inhibitor (5ARI) medication, prostate volume of patients were reviewed and compared with pyuria. The pathologic pattern of inflammation were divided as acute or chronic by
predominant inflammatory cell type; especially, the chronic inflammation was graded according to the extent and severity. Chronic inflammation was determined 102 (46.2%) of 221 in the pathological specimens. Mean value of PSA was 8.3 ng/ml. Mean prostate volume was 64.1 ml 164 (74.2%) patients had prior α1-blocker and 5ARI medication. There was no statistical difference between prostate volume and pyuria. However pyuria was higher relation with prostate size, chronic inflammation and prior medication. Pathologic prostatic inflammation was highly noted in BPH patients when they had white blood cell in urine over 5-7/HPF. Pyuria and prostatic inflammation had highly relationship. Prostatic inflammation must be treated in patients with 5-7/ HPF, white blood cell in urine.
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KEYWORD
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Benign prostatic hyperplasia, Prostatitis, Urinary white blood cell count
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